Synopses & Reviews
In Biochemistry, the questions often are more exhilarating than the answers. This Updated Third Edition continues the unique conceptual and organizing framework, "Essential Questions." Guiding students through the density of the material by the use of section head questions, supporting concept statements, and summaries, this focused approach is supported by unparalleled text/media integration through BiochemistryNow, providing students with a seamless learning system. Beautifully and consistently illustrated, this text gives science majors the most current presentation of biochemistry available. Written by a chemist and a biologist, the book presents biochemistry from balanced perspectives. This Updated Edition includes "Emerging Insights into Biochemistry" at the end of each chapter, which present students with the latest advances in biochemical research. The Updated Edition also is enhanced by the power of the online assessment-centered learning tool, BiochemistryNow. This powerful online learning companion helps students gauge their unique study needs and provides them with a Personalized Learning plan that enhances their problem-solving skills and conceptual understanding.
Synopsis
Continuing Garrett and Grisham's innovative conceptual and organizing framework, "Essential Questions," BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world.The book's balanced presentation has been streamlined for increased clarity and readability--and to make it more interesting to visual learners, this edition also includes new photos and illustrations that show the subject matter consistently throughout the text. New end-of-chapter problems, MCAT practice questions, and the unparalleled text/media integration with the power of CengageNOW round out this exceptional package, giving students the tools they need to master course concepts and develop critical problem-solving skills they can draw upon long after the course ends.
Synopsis
Continuing Garrett and Grisham's innovative conceptual and organizing framework, "Essential Questions," BIOCHEMISTRY guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Streamlined for increased clarity and readability, this edition also includes new photos and illustrations that show the subject matter consistently throughout the text. New end-of-chapter problems, MCAT practice questions, and the unparalleled text/media integration
About the Author
Reginald H. Garrett was educated in the Baltimore city public schools and at the John Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice a Visiting Scholar at the University of Cambridge, and has served as Invited Professor at the University of Toulouse, France.Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became a Professor of Chemistry at the University of Virginia, where he teaches biochemistry and physical chemistry for 34 years. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego, was a Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark for two years, and received a Research Career Development Award from the National Institutes of Health.
Table of Contents
Part I: MOLECULAR COMPONENTS OF CELLS. 1. Chemistry is the Logic of Biological Phenomena. 2. Water - The Medium of Life. 3. Thermodynamics of Biological Systems. 4. Amino Acids. 5. Proteins: Their Primary Structure and Biological Functions. 6. Proteins: Secondary, Tertiary, and Quaternary Structure. 7. Carbohydrates and Glyco-Conjugates of the Cell Surface. 8. Lipids. 9. Membranes and Membrane Transport. 10. Nucleotides and Nucleic Acids. 11. Structure of Nucleic Acids. 12. Recombinant DNA: Cloning and Creation of Chimeric Genes. Part II: PROTEIN DYNAMICS. 13. Enzyme Kinetics. 14. Mechanisms of Enzyme Action. 15. Enzyme Regulation. 16. Molecular Motors. Part III: METABOLISM AND ITS REGULATION. 17. Nutrition and the Organization of Metabolism. 18. Glycolysis. 19. The Tricarboxylic Acid Cycle. 20. Electron Transport and Oxidative Phosphorylation. 21. Photosynthesis. 22. Gluconeogenesis, Glycogen Metabolism, and the Pentose Phosphate Pathway. 23. Fatty Acid Catabolism. 24. Lipid Biosynthesis. 25. Nitrogen Acquisition and Amino Acid Metabolism. 26. The Synthesis and Degradation of Nucleotides. 27. Metabolic Integration and Organ Specialization. Part IV: INFORMATION TRANSFER. 28. DNA Metabolism. 29.Transcription and the Regulation of Gene Expression. 30. Protein Synthesis. 31. Post-Translational Processing of Proteins and Protein Degradation. 32. The Reception and Transmission of Extracellular Information.