Synopses & Reviews
A Practical Introduction to Stereochemistry
Stereoisomers are compounds with the same chemical formula and connectivity but with different arrangements of their atoms in 3-dimensional space. Stereochemistry encompasses the study of stereoisomers and their properties. Despite having an identical chemical formula, stereoisomers can have drastically different biological, medicinal, and chemical properties. Basic Organic Stereochemistry explains in clear, concise terms the concepts and properties of stereoisomers.
Ideal both as a text for advanced undergraduate or graduate students and as a handy guide for researchers in industry, this superb text covers:
* Polarimetry and optical rotation
* Internal coordinates, configuration, and conformation
* Nature of stereoisomers
* Barriers between stereoisomers and residual stereoisomers
* Symmetry operators and symmetry point groups
* Properties of stereoisomers and stereoisomer discrimination
* Separation of stereoisomers, resolution, and racemization
Suitable for students in organic and biological chemistry, Basic Organic Stereochemistry is unparalleled as a convenient text.
Review
"Written for advanced undergraduate students, this book explains the concepts and properties of stereoisomers..." (SciTech Book News, Vol. 25, No. 3, September 2001)
"the book has much to offer to both industrial and academic chemists of all levels." (Synthesis, No.15, 2001)
"this is an excellent well-written textbook that should be in every library" (Organic Process Research & Development)
"a comprehensive and authoritative reference volume - the 'bible' of organic stereochemistry" (Perkin Transactions, No.21, 2001)
"I endorse this book without reservations"
Chemweb book of the week (The Alchemist, 9 April 2002)
Synopsis
Ein kurzgefa tes und bersichtliches, trotzdem aussagekr ftiges und kompetentes Lehrbuch der Stereochemie organischer Verbindungen Behandelt werden vor allem die Grundgedanken und Prinzipien der Konformationsanalyse, Eigenschaften von Stereoisomeren sowie Ans tze zur Isomerentrennung. Erg nzt wird der Text durch viele Beispiele und Aufgaben.
Synopsis
Stereoisomers are compounds with the same chemical formula and connectivity but with different arrangements of their atoms in 3-dimensional space. Stereochemistry encompasses the study of stereoisomers and their properties. Despite having an identical chemical formula, stereoisomers can have drastically different biological, medicinal, and chemical properties. Basic Organic Stereochemistry explains in clear, concise terms the concepts and properties of stereoisomers.
Ideal both as a text for advanced undergraduate or graduate students and as a handy guide for researchers in industry, this superb text covers:
About the Author
ERNEST L. ELIEL, PhD, is W. R. Kenan Jr. Professor Emeritus at the University of North Carolina, Chapel Hill, North Carolina. He is the coauthor of Stereochemistry of Organic Compounds and the recipient of numerous academic and scientific awards. Professor Eliel is past president of the American Chemical Society and a member of the National Academy of Sciences.
SAMUEL H. WILEN, PhD, (deceased) was Professor of Chemistry at City College, City University of New York.
MICHAEL P. DOYLE, PhD, is Vice President of Research Corporation, located in Tucson, Arizona, and Professor of Chemistry at the University of Arizona. He is the recipient of numerous awards for research and teaching.
Table of Contents
Preface.
Introduction.
Structure.
Stereoisomers.
Symmetry.
Configuration.
Properties of Stereoisomers and Stereoisomer Discrimination.
Separation of Stereoisomers, Resolution, and Racemization.
Heterotopic Ligands and Faces: Prostereoisomerism Prochirality.
Stereochemistry of Alkenes.
Conformation of Acyclic Molecules.
Configuration and Conformation of Cyclc Molecules.
Stereoselective Synthesis.
Chiroptical Properties.
Chirality in Molecules Devoid of Chiral Centers.
Glossary.
Index.